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ST. JOHN’S WORT

Botanical Name

  • Family Guttiferae [Hypericaceae]
  • Hypericum perforatum

Common Names

  • Hardhay, Amber, Goatweed, Klamath Weed, Tipton Weed, St. John’s Word, St. Johnswort, Witches’ Herb, Y Fendigedig (Welsh), Balm of Warrior’s Wounds, Devil’s Scourge, Touch and Heal, Lord God’s Wonder Plant, st johns wort, St. John’s wort.

Cautions

It can cause dermatitis or photo-sensitivity after taking it internally and then exposing the skin to the sun.

Contact dermatitis can be caused if handling the plant in moist, but sunny, conditions.

Drug Interactions: Do not take in conjunction with MAOI (monoamine oxidase inhibitors) or other antidepressants, including Prozac, Paxil, Zoloft, lithium, Demerol, or dextromethorphan, a common ingredient in cough syrups. The combination can result in a very dangerous reaction called serotonin syndrome, marked by a high fever, confusion, muscle rigidity, diarrhea, and possible death.

Description

Native to Britain and Europe, the herb now grows wild throughout most of the world. It is found in meadows, on banks, and by roadsides, preferring chalky soils and sunny positions. The herb is an erect perennial that grows to about thirty-two inches and produces bright yellow flowers that form in a flat-topped cluster and display tiny black dots on the petals and sepals. The flowers are harvested in mid-summer.

Key Actions

Key Components

  • glycosides
  • flavonoids (including rutin)
  • volatile oils
  • tannins
  • resins

Medicinal Parts

Aerial parts

A number of Hypericum species contain hypericin, but in smaller quantities than St. John s Wort.

St. John’s Wort and several Hypericum species have shown antitumor activities in animals and at least seventeen species have demonstrated antibacterial properties in vitro. Some species show antifungal activity and at least seven show antiviral properties.

Extracts of H. perforatum have produced antidiarrheal, sedative, antitumor, and diurectic actions.

Hypericin, an active substance in the herb, is thought to increase circulating levels of serotonin, a neurotransmitter instrumental in controlling mood by selectively preventing its reuptake by cells. This mechanism of action is similar to that of Prozac, Zoloft, and other antidepressants. It may also inhibit MAO, a brain enzyme that destroys serotonin, epinephrine, and dopamine, the mood-elevating neurotransmitters.

Remedies

Infusions are used for anxiety, nervous tension, irritability or emotional upsets, especially if associated with menopause or premenstrual syndrome.

Tinctures are taken for at least two months for long-standing nervous tension leading to exhaustion and depression. They are also used in cases of childhood bedwetting.

Washes from infusions are used to bathe wounds, skin sores, and bruises.

Creams made from the flowering tops are used for localized nerve pain (sciatica, sprains, and cramps) or to help relieve breast engorgement during lactation. The cream can also be used as an antiseptic and styptic on scrapes, sores, and ulcers.

Infused oils from the flowering tops can be used on burns and muscle or joint inflammations, including tennis elbow, neuralgia, and sciatica. A few drops of lavender oil can be added for burns, or mixed with yarrow oil to treat joint inflammations.

Traditional Uses

The red color of the infused oil is caused by hypericin, which is strongly antidepressant and so strongly antiviral that it is being researched for treatment of the AIDS virus. It is also an excellent antiseptic, and used on wounds, burns, and to relieve cramps and nerve pain.

It is one of the most valuable European medicinal plants for nervous problems. Herbalists have long used it to treat anxiety, tension, insomnia, and depression especially associated with menopause.

Although widely used to treat depression, it is also helpful in alleviating fatigue and seems effective in helping menstrual cramps and PMS.

There is also some evidence that it can fight HIV. Contemporary herbalists are now using it to treat AIDS and other immunosuppressed conditions.

It is also a valuable tonic for the liver and gallbladder.

Infused oil is useful in treating gastric inflammation and peptic ulcers. Infused oil from these yellow flowers turns a blood-red during the steeping process. Cold-pressed safflower, walnut, or sunflower oil is used then left in the sun for a few weeks (usually about six).

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